Peer-reviewed veterinary case report
Dog with vomiting and weakness diagnosed with rare adrenal lymphoma
By Béguin, J S et al.·Published in The Journal of small animal practice·2020·Department of Internal Medicine, France·View original on PubMed →
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Original publication title: Primary hypoaldosteronism in a dog with pituitary and adrenal T-cell lymphoma.
- Species:
- dog
Plain-English summary
A 7-year-old mixed breed dog was brought to the vet after experiencing vomiting, diarrhea, weakness, and a loss of appetite for two weeks. Tests showed low sodium and high potassium levels, indicating a problem with hormone production. An ultrasound revealed a mass in the left kidney and an enlarged left adrenal gland, which was later identified as a large T-cell lymphoma (a type of cancer). Unfortunately, despite efforts to treat the dog, it passed away 17 days later due to the widespread nature of the cancer affecting multiple organs.
People also search for: dog vomiting and diarrhea · mixed breed dog cancer symptoms · T-cell lymphoma treatment in dogs
Abstract
A 7-year-old mixed breed dog was presented with a 2-week history of vomiting, diarrhoea, weakness and loss of appetite. Initial laboratory tests revealed hyponatraemia and hyperkalaemia consistent with hypoadrenocorticism. Basal plasma cortisol and adrenocorticotropic hormone concentrations were not suggestive of primary hypoadrenocorticism but the aldosterone concentration was undetectable. Abdominal ultrasound scan showed a mass within the left kidney and a nodular enlargement of the left adrenal gland. Cytological analysis revealed a large granular lymphoma. The dog died 17 days later. Post mortem histological and immunohistochemical examinations revealed a diffuse large granular T-cell lymphoma involving the mediastinal lymph node, kidneys, pancreas, adrenal and pituitary glands.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30390298/