Peer-reviewed veterinary case report
Lymphangiosarcoma tumor in a dog's urinary bladder
By Michishita, M et al.·Published in Journal of comparative pathology·2020·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Primary Lymphangiosarcoma of the Urinary Bladder in a Dog.
- Species:
- dog
Plain-English summary
A 12-year-old neutered female toy poodle was found to have a mass in her bladder after abdominal imaging. The mass was about 2 cm in size and was firm with a brownish-yellow appearance. Upon further examination, it was diagnosed as lymphangiosarcoma, a type of cancer that affects the lymphatic vessels. This case is notable as it is the first reported instance of this specific tumor occurring in a dog's bladder. Unfortunately, the abstract does not provide information on treatment or outcome.
People also search for: dog bladder cancer symptoms · toy poodle tumor treatment · lymphangiosarcoma in dogs
Abstract
Abdominal ultrasonographical and computed tomography examinations of a 12-year-old neutered female toy poodle revealed a protruding mass, approximately 2 cm in diameter, at the apex of the bladder. The mass was firm and haemorrhagic with a homogeneously brownish-yellow cut surface. Microscopically, it was unencapsulated and located in the muscle layer with invasion of the extra-muscular layer. It was composed of spindloid to oval neoplastic cells that formed irregular clefts and diffuse sheets that dissected bundles of collagen. Immunohistochemically, the neoplastic cells were positive for vimentin and lymphatic vessel endothelial hyaluronan receptor 1 antigens, but negative for cytokeratin AE1/AE3, factor VIII-related antigen, CD31, CD34, Prox-1, S100, desmin, α-smooth muscle actin and MyoD1. Negative immunolabelling for laminin antigen supported the absence of evidence of a basal lamina on ultrastructural examination. Based on these findings, this tumour was identified as a lymphangiosarcoma. To the best of our knowledge, this case is the first report of lymphangiosarcoma arising from the bladder in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32958144/