Peer-reviewed veterinary case report
Dog with muscle lymphoma and skin lumps on head
By Lopes, Mariana G et al.·Published in Veterinary clinical pathology·2021·School of Veterinary Medicine, United Kingdom·View original on PubMed →
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Original publication title: Primary multifocal muscular T-cell lymphoma with cutaneous involvement in a dog: A case report and review of the literature.
- Species:
- dog
Plain-English summary
A 5-year-old female neutered Beagle was brought to the vet because she had a lump in her right shoulder, was limping, and seemed lethargic. After a month, she developed several nodules on her head, prompting further tests that revealed she had a rare type of cancer called peripheral T-cell lymphoma affecting her muscles and skin. Unfortunately, due to the poor prognosis associated with this condition, the decision was made to euthanize her. This case highlights the importance of considering lymphoma when a dog presents with unusual muscle masses.
People also search for: dog shoulder lump · Beagle cancer symptoms · lymphoma in dogs treatment
Abstract
Canine lymphoma represents a heterogeneous group of lymphoid neoplasms, with multicentric nodal lymphoma being the most common presentation. Musculoskeletal involvement is uncommon, and primary muscular lymphoma is a very rare presentation. Only a few cases have been described in dogs, which were of variable classification and immunophenotype. Here, we report the case of a 5-year-old female neutered Beagle that presented with an intramuscular mass on the right shoulder and associated lameness and lethargy. One month after initial presentation, multiple cutaneous nodules appeared on the head, and staging with advanced imaging revealed additional masses affecting other muscles. Cytology, histopathology, immunohistochemistry, and PCR for antigen receptor rearrangements of one of the muscle masses and skin lesions supported a diagnosis of peripheral T-cell lymphoma with large granular lymphocytes at both sites. The dog was euthanized after diagnosis due to the poor prognosis. This is the first report of primary muscular peripheral T-cell lymphoma with large granular lymphocytes and cutaneous involvement in the dog. Despite being a rare presentation, lymphoma must be considered a differential in dogs presenting with a discrete, intramuscular, soft tissue mass.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34693549/