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Peer-reviewed veterinary case report

Nasal histiocytic sarcoma causing a mass in a 16-year-old cat

By Wong, V M et al.·Published in Journal of comparative pathology·2012·Department of Pathobiology, Canada·View original on PubMed

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Original publication title: Primary nasal histiocytic sarcoma of macrophage-myeloid cell type in a cat.

Species:
cat

Plain-English summary

A 16-year-old neutered male Burmese cat was brought to the vet because of a growth in its nose. After a biopsy, the results showed that the mass was a type of cancer called histiocytic sarcoma, which is a tumor made up of certain immune cells. Sadly, further examination after the cat passed away revealed that the cancer had spread to the bone marrow. This case highlights the importance of considering histiocytic sarcoma when a cat has a nasal mass.

People also search for: cat nasal mass cancer · Burmese cat tumor treatment · histiocytic sarcoma in cats

Abstract

A 16-year-old neutered male Burmese cat was presented with a locally invasive nasal mass. The cytological and histological findings on incisional biopsy of this mass were suggestive of histiocytic sarcoma. Tumour cells expressed CD18, major histocompatibility complex class II, lysozyme and alpha-naphthyl acetate esterase; and lacked expression of CD3, CD79a, CD1a, CD1b, calprotectin, CD11c and E-cadherin. These findings are consistent with a myeloid-macrophage lineage. Metastasis to the bone marrow was present on necropsy examination. Histiocytic sarcoma should be considered in cats presented with primary round cell neoplasia of the nasal cavity.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22520253/