Peer-reviewed veterinary case report
Skin neuroblastoma tumor in an adult Shih Tzu dog
By Michishita, Masaki et al.·Published in Veterinary dermatology·2010·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Primary neuroblastoma in the skin of an adult shih tzu dog.
- Species:
- dog
Plain-English summary
An 11-year-old female shih tzu was found to have a lump in her right hip area, which turned out to be a rare type of tumor called neuroblastoma. The mass was surgically removed, and tests confirmed the diagnosis. This case is notable because it's the first time a neuroblastoma has been reported in the skin of an adult dog. While the abstract does not mention the outcome after surgery, typically, early detection and removal of tumors can lead to better health for pets.
People also search for: shih tzu skin tumor · dog neuroblastoma treatment · lump on dog hip · dog surgery for tumor
Abstract
A subcutaneous mass arising in the right gluteal area of an 11-year-old female shih tzu dog was surgically excised. Histologically, the mass was composed of small round or ovoid neoplastic cells that were arranged in nests of various sizes. The neoplastic cells generally had hyperchromatic nuclei and scanty eosinophilic cytoplasm, and were surrounded by a pale pink fibrillar area. Immunohistochemically, the neoplastic cells were positive for vimentin, S-100 protein, neurone-specific enolase and synaptophysin, but negative for cytokeratin, neurofilament protein, glial fibrillary acidic protein and chromogranin A. On ultrastructural observation, aggregates of thin cytoplasmic processes were frequently seen among the neoplastic cells. Based on these features, the tumour was diagnosed as a neuroblastoma. To the authors' knowledge, this is the first description of a neuroblastoma originating from the skin in an adult dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20230584/