Peer-reviewed veterinary case report
Safe and effective canine parvovirus vaccine tested in Morocco
By Sebbar, Ghizlane et al.·Published in Vaccines·2024·Société de Productions des Produits Biologiques & Vétérinaires, Avenue Hassan II, Rabat 10051, Morocco·View original on Crossref →
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Original publication title: Production and Evaluation of an Inactivated Adjuvanted Vaccine against Canine Parvovirus in Morocco
- Species:
- dog
Plain-English summary
A group of puppies in Morocco were vaccinated against canine parvovirus (CPV-2), a serious illness that can cause severe vomiting and diarrhea. The vaccine was made from a strain of the virus taken from a sick dog and was tested for safety and effectiveness. The vaccinated puppies showed no side effects and remained healthy, with less virus in their systems compared to those that weren't vaccinated. This suggests that the vaccine is a good option for protecting dogs from CPV-2 and helps control outbreaks of this dangerous virus.
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Abstract
The study conducted in Morocco focused on addressing the challenges posed by canine parvovirus (CPV-2) through comprehensive research, vaccine development, and efficacy assessment. Through real-time PCR screening and genotyping, CPV-2 variants were identified circulating in the region. An inactivated vaccine, derived from a CPV-2 strain isolated from a symptomatic dog, was produced and evaluated for safety and efficacy. The vaccine, from the strain named “CaPV M/3-2022”, demonstrated safety in vaccinated puppies, with no adverse reactions observed during the trial period. Efficacy trials showed that vaccinated puppies remained healthy and exhibited lower viral excretion post-challenge compared to unvaccinated controls. These results indicate that the vaccine effectively protects against illness related to CPV-2 and reduces viral shedding. The study provides valuable insights into CPV-2 epidemiology in Morocco, offers a promising vaccine solution, and underscores the importance of vaccination in controlling CPV-2 outbreaks and protecting canine health.
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Search related cases →Original publication on Crossref: https://doi.org/10.3390/vaccines12090995