Peer-reviewed veterinary case report
Factors affecting survival in cats with nasal squamous cell carcinoma
By Lino, Mafalda et al.·Published in Journal of feline medicine and surgery·2019·Department of Veterinary Sciences·View original on PubMed →
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Original publication title: Prognostic factors for cats with squamous cell carcinoma of the nasal planum following high-dose rate brachytherapy.
- Species:
- cat
Plain-English summary
A group of 58 cats with squamous cell carcinoma (a type of skin cancer) on their noses received high-dose rate brachytherapy, a specialized radiation treatment. Most of the cats showed improvement, with 72% achieving complete response and 24% showing partial response. The average time before the cancer progressed was about 316 days, and overall survival was around 835 days. Factors like the size of the tumor and whether it had spread affected the outcomes, but the treatment was generally effective in helping these cats.
People also search for: cat nose cancer treatment · squamous cell carcinoma in cats · brachytherapy for cats · cat cancer survival rates
Abstract
OBJECTIVES: The aim of the study was to investigate retrospectively the prognostic impact of variables such as sex, neuter status, breed, age, number of lesions, location and size of the tumour, tumour extension beyond the nasal planum, ulceration and lymph node status, among others, in a population of cats treated with high-dose rate brachytherapy. METHODS: This study reviews the outcome of 58 cats with cytologically and/or histologically confirmed squamous cell carcinoma of the nasal planum, treated at the Clinic Alliance (Bordeaux, France) with high-dose rate brachytherapy from 2010-2016. The total radiation dose delivered was 30 Gy, administered in two different schedules: five fractions of 6 Gy for a period of 4 days (Tuesday-Friday) or four fractions of 7.5 Gy for a period of 3 days (Tuesday- Thursday). Data were collected from cats' clinical records. RESULTS: Complete response was achieved in 72% (n = 36) of the cats, partial response in 24% (n = 13) and 2% (n = 1) did not respond. Median progression-free survival and overall survival times were 316 and 835 days, respectively. CONCLUSIONS AND RELEVANCE: Results indicated that sex (= 0.045), extension of the tumour from the nasal planum to the upper lip (= 0.015), tumour size (= 0.015;= 0.001), the existence of a previous treatment (= 0.043) and the tumour response to high-dose rate brachytherapy (= 0.038;<0.001) are prognostic factors for cats with squamous cell carcinoma of the nasal planum following high-dose rate brachytherapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30667286/