Prognostic Factors for Injection-Site Sarcomas in Cats.

Abstract

In this retrospective study of cases from Italy and Switzerland, the clinical features of injection-site sarcomas in 57 cats were reviewed. In addition to routine physical, laboratory, and radiographic examinations, advanced imaging (computed tomographic scans) was conducted to delineate tumor extent. Treatment was by wide surgical excision including partial scapulectomy, spinous process removal, and amputation (appendicular lesions). Radiotherapy and chemotherapy were also used. The results revealed that cats with grade 3 tumors were most likely to develop distant pulmonary metastases (and to have shorter survival rates); this occurred in 21% of the cases.Median follow-up for cats that survived (51%) was 600 days; for those that died (49%), it was 272 days. In this study, tumor size, as measured manually by calipers, was not a prognostic factor. Furthermore, factors associated with local recurrence were not identified. The authors recognized the limitations of a retrospective study, especially with regard to treatments before referral.