Peer-reviewed veterinary case report
Young English bulldog with bleeding and immune protein disorder
By Grady, Jennifer L et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2021·Tufts University, United States·View original on PubMed →
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Original publication title: Progressive gammopathy and coagulopathy in a young English bulldog.
- Species:
- dog
Plain-English summary
A young, neutered male English bulldog was brought in with bleeding problems, an enlarged spleen, and low red blood cell counts. Tests showed high levels of certain antibodies, indicating a condition called gammopathy, which can cause bleeding tendencies. The veterinarian treated him with prednisone and chlorambucil, and he responded well to the treatment. After starting the medications, the dog's condition improved, and he was able to recover from the bleeding issues.
People also search for: English bulldog bleeding problems · dog gammopathy treatment · prednisone for dog bleeding disorder
Abstract
A restricted polyclonal or biclonal gammopathy resulting in bleeding tendencies was diagnosed in a young, neutered male English bulldog with concurrent splenomegaly, anemia, and severe elevations in IgM and, to a lesser degree, IgA immunoglobulins. There was a positive clinical response to treatment with prednisone and chlorambucil. This case bears similarity to a recently published syndrome of polyclonal gammopathy that is not neoplastic in origin in this breed. Key clinical message: The current case describes the management and clinical course of a recently described syndrome of polyclonal gammopathy in English bulldogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33542555/