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Peer-reviewed veterinary case report

Beagle dog with worsening jerking seizures and Lafora disease

By Gredal, H et al.·Published in The Journal of small animal practice·2003·Department of Clinical Sciences·View original on PubMed

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Original publication title: Progressive myoclonus epilepsy in a beagle.

Species:
dog

Plain-English summary

A 9-year-old female beagle was brought in because she was experiencing worsening jerking movements of her head and front legs, especially when there were changes in light, noise, or movement. She also seemed mentally depressed. Tests showed that she had a type of epilepsy called myoclonus epilepsy. Unfortunately, after she passed away, further examination revealed that she had Lafora's disease, a serious condition affecting the brain.

People also search for: beagle myoclonus epilepsy symptoms · dog jerking movements treatment · Lafora's disease in dogs

Abstract

A nine-year-old, neutered female beagle was presented with a history of progressive myoclonic jerks. Clinical signs included mental depression and paroxysmal jerks of the head and forelimbs, apparently elicited by changes in light, noise or movements. Electroencephalographic findings were in accordance with myoclonus epilepsy. Postmortem histopathological findings included multiple periodic acid-Schiff-positive inclusion bodies throughout the central nervous system, but especially in the cerebellum, confirming the suspected diagnosis of Lafora's disease.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14635965/