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Peer-reviewed veterinary case report

Protein-losing kidney disease linked to Lyme in a wheaten terrier

By Horney, Barbara S & Stojanovic, VladimirĀ·Published in The Canadian veterinary journal = La revue veterinaire canadienneĀ·2013Ā·Department of Pathology and Microbiology (Horney) and Department of Companion Animals (Stojanovic)Ā·View original on PubMed →

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Original publication title: Protein-losing nephropathy associated with Borrelia burgdorferi seropositivity in a soft-coated wheaten terrier: response to therapy.

Species:
dog

Plain-English summary

A soft-coated wheaten terrier was brought to the vet for lameness and was found to have protein-losing nephropathy (a kidney issue that causes protein loss in urine) along with low albumin levels and a positive test for Lyme disease (caused by Borrelia burgdorferi). After starting treatment with doxycycline, the dog's urine protein loss significantly decreased, and its albumin levels stabilized within a normal range for over three years. This is a positive outcome, especially since kidney issues related to Lyme disease typically have a poor prognosis.

People also search for: soft-coated wheaten terrier kidney disease Ā· dog lameness treatment Ā· doxycycline for Lyme disease in dogs

Abstract

A soft-coated wheaten terrier was examined for lameness with subsequent identification of protein-losing nephropathy, hypoalbuminemia, hyperglobulinemia, and seroconversion to Borrelia burgdorferi. Following doxycycline therapy, the urine protein loss decreased significantly and serum albumin concentration remained close to or within the reference interval for over 3 years, contrary to the reported poor prognosis for renal disease associated with B. burgdorferi or protein-losing nephropathy of soft-coated wheaten terriers.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24082169/