Peer-reviewed veterinary case report
Protein in urine linked to gallbladder mucus buildup in dogs
By Lindaberry, Crystal et al.·Published in Journal of veterinary internal medicine·2021·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Proteinuria in dogs with gallbladder mucocele formation: A retrospective case control study.
- Species:
- dog
Plain-English summary
A group of dogs with gallbladder mucocele (a buildup of mucus in the gallbladder) showed higher levels of protein in their urine compared to healthy dogs of similar age and breed. This proteinuria (excess protein in urine) can indicate potential kidney issues and was linked to the severity of their illness. Recognizing and treating proteinuria in dogs with gallbladder mucocele could help reduce long-term kidney problems. If your dog has been diagnosed with a gallbladder mucocele, it’s important to discuss urine testing and possible treatments with your veterinarian.
People also search for: dog gallbladder mucocele symptoms · protein in dog urine treatment · dog kidney problems and gallbladder issues
Abstract
BACKGROUND: Proteinuria is an independent risk factor for morbidity and mortality in dogs. An association between proteinuria and gallbladder mucocele formation in dogs is unknown. OBJECTIVE: Determine if gallbladder mucocele formation or clinicopathologic comorbidities are associated with proteinuria. ANIMALS: Twenty-five dogs with mucocele formation and 25 breed and age-matched control dogs from a prior study. METHODS: Retrospective case control study. Proteinuria defined by calculated urine dipstick protein concentration (mg/mL) to urine specific gravity (USG) ratio. Clinicopathologic findings, postcosyntropin cortisol concentration, thyroid function profile, and illness severity score were recorded. RESULTS: Median urine dipstick protein concentration to USG ratio and number of dogs having a ratio ≥1.5 were significantly higher for dogs with mucocele formation compared to control dogs. Proteinuria was not significantly associated with CBC or serum biochemistry profile abnormalities but increased in relation to severity of illness. CONCLUSIONS AND CLINICAL IMPORTANCE: Gallbladder mucocele formation is significantly associated with proteinuria in dogs. Diagnosis and treatment of proteinuria in dogs with mucocele formation might minimize long term kidney morbidity in these patients.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33547696/