Peer-reviewed veterinary case report
Protein in urine linked to gallbladder mucus buildup in dogs
By Crystal Lindaberry et al.·Published in Journal of Veterinary Internal Medicine·2021·Department of Clinical Sciences North Carolina State University Raleigh North Carolina USA, GB·View original on DOAJ →
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Original publication title: Proteinuria in dogs with gallbladder mucocele formation: A retrospective case control study
- Species:
- dog
Plain-English summary
A group of 25 dogs with gallbladder mucocele (a condition where the gallbladder fills with thick mucus) showed higher levels of protein in their urine compared to 25 similar dogs without this condition. This proteinuria (excess protein in urine) could indicate a risk for kidney problems. The study suggests that recognizing and treating proteinuria in dogs with gallbladder mucocele may help protect their kidneys in the long run. If your dog has been diagnosed with gallbladder mucocele, it might be worth discussing urine testing and treatment options with your vet.
People also search for: dog gallbladder mucocele treatment · protein in dog urine causes · dog kidney health with gallbladder issues
Abstract
Abstract Background Proteinuria is an independent risk factor for morbidity and mortality in dogs. An association between proteinuria and gallbladder mucocele formation in dogs is unknown. Objective Determine if gallbladder mucocele formation or clinicopathologic comorbidities are associated with proteinuria. Animals Twenty‐five dogs with mucocele formation and 25 breed and age‐matched control dogs from a prior study. Methods Retrospective case control study. Proteinuria defined by calculated urine dipstick protein concentration (mg/mL) to urine specific gravity (USG) ratio. Clinicopathologic findings, postcosyntropin cortisol concentration, thyroid function profile, and illness severity score were recorded. Results Median urine dipstick protein concentration to USG ratio and number of dogs having a ratio ≥1.5 were significantly higher for dogs with mucocele formation compared to control dogs. Proteinuria was not significantly associated with CBC or serum biochemistry profile abnormalities but increased in relation to severity of illness. Conclusions and Clinical Importance Gallbladder mucocele formation is significantly associated with proteinuria in dogs. Diagnosis and treatment of proteinuria in dogs with mucocele formation might minimize long term kidney morbidity in these patients.
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Search related cases →Original publication on DOAJ: https://doi.org/10.1111/jvim.16051