Peer-reviewed veterinary case report
Proteomics in the search for biomarkers of animal cancer.
- Journal:
- Current protein & peptide science
- Year:
- 2014
- Authors:
- Kycko, Anna & Reichert, Michal
Plain-English summary
Cancer is becoming more common in pets, leading to many deaths in recent years. Just like in people, it's important for veterinarians to find ways to prevent cancer, diagnose it early, and treat it effectively. Researchers are looking for specific proteins in the body that could help identify cancer early and track how well treatments are working. The paper discusses the progress made in using these protein studies to find cancer markers in animals, which could improve how we diagnose and treat cancer in pets.
Abstract
The prevalence of cancer in companion animals has increased in the recent decade, making this disease one of the major causes of deaths. As in human medicine, veterinary medicine faces the problem of cancer prevention as well as early diagnosis and effective therapy. Early diagnosis of cancer is crucial for the successful treatment of the disease and there is a need for biomarkers that could be used as a diagnostic tool, and to guide a targeted therapy or monitor a therapeutic response. Proteomic technologies that were introduced to human cancer research over a decade ago provide the opportunity to identify distinct protein patterns for cancer diagnosis and therapy monitoring. These also have potential to be utilised in veterinary medicine. The present paper summarises the current knowledge about proteomic studies on animal cancer biomarker research published to date.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24555898/