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Peer-reviewed veterinary case report

Cat with coughing and lung nodules diagnosed with pulmonary

By Valentine, B A et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2000·Department of Biomedical Sciences, United States·View original on PubMed

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Original publication title: Pulmonary lymphomatoid granulomatosis in a cat.

Species:
cat

Plain-English summary

A 9-year-old male domestic shorthair cat was brought to the vet for coughing, lethargy, and not eating. X-rays showed multiple spots in the lungs and swollen lymph nodes in the chest. Tests on lung tissue revealed abnormal cells, indicating a rare condition called pulmonary lymphomatoid granulomatosis, which involves an aggressive type of immune response in the lungs. Unfortunately, the outcome of treatment for this condition isn't specified, but it's important for pet owners to discuss any similar symptoms with their veterinarian for proper diagnosis and care.

People also search for: cat coughing lethargy not eating · cat lung disease symptoms · pulmonary lymphomatoid granulomatosis treatment

Abstract

Pulmonary lymphomatoid granulomatosis was diagnosed in a 9-year-old castrated male domestic shorthair cat with a history of coughing, lethargy, and anorexia. Radiographic examination revealed multiple pulmonary opacities, consolidation of left lung lobes, and enlarged tracheobronchial lymph nodes. Cytologic examination of impression smears of abnormal pulmonary tissue revealed erythrocytes, lymphocytes, and macrophages, with scattered atypical lymphocytes and binucleate cells. Histopathologic evaluation of abnormal lung tissue revealed multiple, coalescing, densely cellular nodules composed of anaplastic and pleomorphic lymphocytes, with scattered binucleate and multinucleate cells. Marked infiltration and effacement of bronchiolar and vascular smooth muscle were present. These features are characteristic of lymphomatoid granulomatosis. To the authors' knowledge, this is the first report of pulmonary lymphomatoid granulomatosis in a cat.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11021438/