Peer-reviewed veterinary case report
Cat with breathing trouble after vincristine chemo treatment
By Polton, Gerry A & Elwood, Clive M·Published in Veterinary journal (London, England : 1997)·2008·Oncology Department, United Kingdom·View original on PubMed →
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Original publication title: Pulmonary oedema as a suspected adverse drug reaction following vincristine administration to a cat: a case report.
- Species:
- cat
Plain-English summary
A cat with chronic lymphocytic leukemia experienced trouble breathing after receiving a chemotherapy drug called vincristine. Initially, the treatment worked well, but about four months later, the cat developed respiratory distress within hours of the vincristine dose. Emergency treatment helped the cat recover fully each time, but the breathing problems recurred with subsequent doses of vincristine, suggesting it was an adverse reaction to the medication. The vet was able to manage the situation, ensuring the cat's safety during treatment.
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Abstract
This report describes recurrent respiratory distress following vincristine administration to a cat with chronic lymphocytic leukaemia. The cat was treated with a combination of vincristine, chlorambucil and prednisolone with initial success. After approximately 4 months, dyspnoea developed within 6 h of vincristine administration. Emergency therapy was instituted resulting in a full recovery. Further vincristine was administered; dyspnoea was similarly noted after all but one of these treatments. Dyspnoeic episodes were not attributable to alterations in vincristine dose or method of administration. The repeated temporal association was consistent with a suspected adverse drug reaction to vincristine.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17555995/