Peer-reviewed veterinary case report
Cat with lung sarcomatoid carcinoma and arterial blood clot
By Aria L Guarino et al.·Published in Case Reports in Veterinary Medicine·2021·View original on Semantic Scholar →
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Original publication title: Pulmonary Sarcomatoid Carcinoma Associated with Arterial Thromboembolism in a Cat
- Species:
- cat
Plain-English summary
A 14-year-old neutered male domestic shorthair cat was brought in because he suddenly couldn't use one of his back legs. The vet found signs of a blood clot in the arteries and noticed lung problems on X-rays. Sadly, a necropsy revealed a serious lung tumor that was a mix of different cancer types. This case is notable because it's the first time this specific type of tumor has been reported in a cat, and it was linked to the blood clot issue. Unfortunately, the cat did not survive due to the severity of the condition.
People also search for: cat sudden leg weakness · cat lung tumor symptoms · cat blood clot treatment
Abstract
A 14-year-old, neutered male domestic shorthair cat presented for acute monoparesis with physical exam findings and biochemical data supportive of a distal arterial thromboembolism. Thoracic radiographs revealed an alveolar pattern in the right middle lung lobe and multifocal nodules in other lung lobes. A pulmonary mass was found on necropsy, which was composed of both carcinomatous and sarcomatous components, confirmed with cytokeratin and vimentin immunohistochemistry. Using the World Health Organization classification scheme for mixed pulmonary tumors, this tumor would be characterized as a pleomorphic squamous cell carcinoma under the umbrella term of pulmonary sarcomatoid carcinoma. The World Health Organization classification of mixed pulmonary tumors and its application to previously reported mixed pulmonary tumors in companion animals is discussed. This is the first reported case of this tumor type in a cat, as well as the first report of this tumor type associated with an arterial thromboembolism in any veterinary species.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/33510928