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Peer-reviewed veterinary case report

Cat with rare skin disease linked to intestinal T-cell lymphoma

By Mendoza-Kuznetsova, Ekaterina et al.·Published in Veterinary dermatology·2026·Cummings School of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Putative Paraneoplastic Pemphigus in a Cat With T-Cell Intestinal Lymphoma.

Species:
cat
LymphomaStomach & digestionCats

Plain-English summary

A 10-year-old domestic shorthair cat was diagnosed with a rare autoimmune skin condition called paraneoplastic pemphigus, which was linked to intestinal T-cell lymphoma (a type of cancer). The cat showed severe skin problems, including painful blisters and sores. Treatment focused on managing the lymphoma, which helped improve the cat's skin condition. While the case is unique, it highlights the connection between certain cancers and autoimmune diseases in pets.

People also search for: cat skin problems · cat intestinal lymphoma treatment · autoimmune skin disease in cats

Abstract

Paraneoplastic pemphigus (PNP) is a rare, severe autoimmune condition. The single published feline case of PNP was associated with lymphocytic thymoma. This case report describes a cat with PNP associated with intestinal T-cell lymphoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41607245/