Peer-reviewed veterinary case report
Pyrazolopyranopyrimidines as a class of anti-inflammatory agents.
- Journal:
- Zeitschrift fur Naturforschung. C, Journal of biosciences
- Year:
- 2006
- Authors:
- Zaki, Magdy E A et al.
- Affiliation:
- Photochemistry Department
Abstract
Pyrazolopyranopyrimidines 6a-c and 8a-c were prepared from the reaction of compounds 4a-c or 7a-c with methylamine or ammonium hydroxide solutions. Treatment of compounds 6a-c or 8a-c with 2-chloroethyl methyl ether afforded their corresponding acyclonucleosides 9a-c or 10a-c, respectively, as a new class of acyclonucleosides. All prepared compounds were tested as anti-inflammatory agents and some of them revealed moderate to potent anti-inflammatory activity.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16610208/