Peer-reviewed veterinary case report
Pony with nasal lymphoma treated with radiation therapy - what to
By Gerard, Mathew et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2010·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Radiation therapy communication: nasal passage and paranasal sinus lymphoma in a pony.
- Species:
- horse
Plain-English summary
A pony with nasal passage and sinus lymphoma was treated with palliative radiation therapy to help manage the cancer. The treatment involved two sessions of radiation, and within two months, the tumor shrank significantly. Remarkably, the pony remained free of any signs of the disease for 2.5 years after the treatment. While the pony experienced temporary blindness shortly after the second session, it wasn't confirmed to be caused by the radiation. Overall, the treatment improved the pony's quality of life and showed that radiation can be effective for this type of cancer in horses.
People also search for: pony nasal cancer treatment · radiation therapy for horse lymphoma · pony sinus tumor symptoms
Abstract
An aged pony with extensive paranasal sinus and nasal passage B-cell lymphoma was treated with palliative radiation therapy. Sixteen gray were administered in two fractions, 7 days apart. A lateral field was used for the first fraction and a dorsal field for the second. Because of tumor being present in the left frontal sinus, gross tumor was knowingly excluded from the treated volume in the lateral field. The tumor regressed within 2 months and the pony remained free of clinical disease for 2.5 years. Acute, temporary blindness developed shortly after the second radiation fraction, but a direct causal relationship with the radiation therapy was not confirmed. The only radiation side effect was leukotrichia. Palliative treatment was successful in improving and prolonging the quality of life. These results suggest that localized equine B-cell lymphoma is radiosensitive, and that palliative radiation therapy is a reasonable consideration for large tumors, even when tumor volume prevents all gross tumor from being irradiated.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20166403/