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Peer-reviewed veterinary case report

Radiotherapy of a recurrent ossifying fibroma in the paranasal sinuses of a horse.

Journal:
Journal of the American Veterinary Medical Association
Year:
2004
Authors:
Orsini, James A et al.
Affiliation:
Department of Clinical Studies-New Bolton Center · United States
Species:
horse

Plain-English summary

A 7-year-old female Thoroughbred horse was having trouble breathing, making a wheezing sound, and was unable to exercise well. After a check-up, the vet found a growth in her left paranasal sinuses (the spaces around the nose) that turned out to be an ossifying fibroma, a type of tumor. The first attempt to treat it involved surgery to remove the tumor, but it came back after 9 months. The horse had a second surgery, followed by radiation treatment, and the tumor did not return for over 6 years. After a third surgery and more radiation, the tumor stayed away for another 3 years. This case suggests that using radiation after surgery can help keep this type of tumor from coming back in horses.

Abstract

A 7-year-old female Thoroughbred was admitted with a history of labored breathing, stridor, and exercise intolerance. Examination revealed a mass in the left paranasal sinuses that was determined to be an ossifying fibroma. Initial treatment consisted of surgical removal of the mass alone; however, the mass recurred 9 months after surgery. The mass was again removed, and adjunctive radiotherapy consisting of 3,000 cGy of cobalt radiation was administered. This time, the tumor did not recur for > 6 years. A third surgery was performed to remove the mass, and adjunctive radiotherapy consisting of 4,000 cGy of photon beam radiation from a linear accelerator was administered. The mass did not recur during the subsequent 3 years. Ossifying fibromas are uncommon tumors that frequently recur if incompletely excised. Results in this horse suggest that adjunctive radiotherapy may delay or prevent tumor recurrence in affected horses.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15124891/