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Peer-reviewed veterinary case report

Radiation therapy helped two cats with pituitary tumors

By Kaser-Hotz, B et al.·Published in Schweizer Archiv fur Tierheilkunde·2000·Veterin&#xe4·View original on PubMed

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Original publication title: [Radiation therapy in two cats with pituitary tumors].

Species:
cat

Plain-English summary

Two cats with pituitary tumors were treated with radiation therapy to help reduce their symptoms. One cat had a complete response to the treatment, while the other showed partial improvement. Both cats tolerated the anesthesia well, and side effects were minimal and temporary. Unfortunately, one cat was later euthanized due to an unrelated illness, and the other was euthanized because the tumor came back. Overall, the radiation therapy was effective in managing their conditions.

People also search for: cat pituitary tumor treatment · cat radiation therapy side effects · cat tumor recurrence after treatment

Abstract

Two cats with large pituitary neoplasms (adenoma and adenocarcinoma) were treated with fractionated radiation therapy. Total doses of 40 Gy, respectively 36 Gy, were applied in 10 fractions of 4 Gy, and 3.6 Gy respectively. Side effects were minimal and transient. Anesthesia was well tolerated. Improvement of clinical signs could be observed during radiation therapy in both cats. One cat had a complete, the other a partial tumor response. One cat (suspicion of adenoma) was euthanized 1 3/4 years after therapy due to unrelated disease. No tumor was found on histopathology, however a small focal necrosis of brain tissue in the irradiated field was observed. The second animal with a pituitary adenocarcinoma was euthanized because of tumor recurrence 1 1/2 years after therapy. Radiation therapy was effective, despite the low total doses of radiation applied.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11103615/