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Peer-reviewed veterinary case report

Radioactive gold seed treatment for cat eyelid cancer

By Hardman, C & Stanley, R·Published in Australian veterinary journal·2001·Animal Eye Care·View original on PubMed

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Original publication title: Radioactive gold-198 seeds for the treatment of squamous cell carcinoma in the eyelid of a cat.

Species:
cat

Plain-English summary

A 19-year-old domestic short-hair cat was brought in with a large, bleeding tumor on her left lower eyelid that had been present for three months. After confirming it was squamous cell carcinoma (a type of skin cancer), the veterinarian decided to treat it with radioactive gold-198 seeds. Nine seeds were implanted, and within three weeks, the tumor had mostly resolved, leaving only a small scab. By six weeks, there was no sign of the tumor, and although some eyelid margin was missing, the cat only experienced mild conjunctivitis. Ten months later, there was still no evidence of the tumor when the cat was euthanized for unrelated health issues.

People also search for: cat eyelid tumor treatment · squamous cell carcinoma in cats · radioactive gold seeds for cat cancer

Abstract

A 19-year-old, speyed, domestic short-hair cat was presented with an eyelid tumour of 3 months duration. Ophthalmic examination revealed a large, raised, ulcerated and bleeding mass affecting the left lower eyelid. The mass was 12 mm x 10 mm in size, extended to the medial canthus and had eroded 10 mm of eyelid margin. Mandibular lymph nodes were not palpably enlarged. A diagnosis of squamous cell carcinoma was confirmed by histologic examination. Due to involvement of more than half the lower eyelid, it was decided that treatment with radioactive gold-198 seeds was appropriate. Nine radioactive gold-198 seeds were implanted, delivering a minimum tumour dose of 65 Gy. Three weeks postoperatively the mass had resolved, with only a small scab remaining. After a further 3 weeks, there was no evidence of the eyelid tumour. Although approximately 7 mm of eyelid margin was absent, this did not cause any clinical signs other than mild conjunctivitis. There was no evidence of the tumour 10 months postoperatively, when the cat was euthanased for unrelated disease.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11702929/