Peer-reviewed veterinary case report
Radiation treatment for localized oral lymphoma in dogs survival
By Berlato, D et al.·Published in Veterinary and comparative oncology·2012·Animal Health Trust, United Kingdom·View original on PubMed →
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Original publication title: Radiotherapy in the management of localized mucocutaneous oral lymphoma in dogs: 14 cases.
- Species:
- dog
Plain-English summary
A group of 14 dogs with localized oral lymphoma, a rare type of cancer affecting the mouth, were treated with radiation therapy after surgery and chemotherapy failed to provide long-term relief. The dogs showed a good response to the treatment, with about 67% experiencing either complete or partial remission. On average, these dogs lived for over three years after starting radiation, especially those without lymph node involvement. Overall, radiation therapy proved to be a well-tolerated and effective option for managing this condition.
People also search for: dog oral lymphoma treatment · radiation therapy for dogs · localized lymphoma in dogs · dog cancer survival rates
Abstract
Oral mucocutaneous lymphoma is rare in dogs. Surgery and chemotherapy do not usually provide effective long-term control. The objective of this study was to retrospectively evaluate survival of dogs with localized oral lymphoma treated with radiation therapy. The medical database of three institutions was searched for dogs with diagnosis of oral lymphoma treated with radiotherapy. Dogs with evidence of systemic disease were excluded. Survival was calculated with the Kaplan-Meier method and prognostic variables analysed with log-rank test. Fourteen dogs were included in the study. Mean survival was 1129 days [95% confidence interval (CI) 711-1546] with median survival of 770 days. The overall response of radiotherapy was 67% (five complete and three partial responses). A survival advantage was seen in dogs with no evidence of lymph node metastasis (P = 0.002) and that achieved a complete response to radiation therapy (P = 0.013). Radiation therapy was a well-tolerated and effective treatment for localized oral lymphoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22236033/