Peer-reviewed veterinary case report
Dog's kidney function worsened quickly after hydroxyethyl starch
By Bae, Junwoo et al.·Published in The Journal of veterinary medical science·2017·College of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Rapid exacerbation of renal function after administration of hydroxyethyl starch in a dog.
- Species:
- dog
Plain-English summary
A 4-year-old male Golden Retriever developed kidney problems after receiving a treatment called hydroxyethyl starch (HES) to help with fluid buildup in his abdomen. Initially, the dog had mild kidney issues, but his condition worsened rapidly after a few days on HES. A closer examination of his kidneys showed significant damage, confirming that HES can be harmful to a dog's kidneys. This case highlights the potential risks of using HES in dogs, especially for those with existing kidney concerns.
People also search for: dog kidney problems after treatment · hydroxyethyl starch side effects in dogs · Golden Retriever kidney injury symptoms
Abstract
Hydroxyethyl starches (HES) are commonly used synthetic colloidal solution in veterinary medicine. Despite of possible adverse effect to kidney injury in human, there is no report about nephrotoxic effects of HES in dogs. HES was administered to a Golden retriever (4-year-old, intact male) with ascites in order to increase plasma osmolality. Initially, the dog was mild azotemic, however, kidney function was rapidly deteriorated after several days of HES administration. Finally, histopathological examination revealed remarkable osmotic nephrosis. In the case reported herein, acute kidney injury was remarkably developed after HES administration. Clinical and histopathologic findings of acute kidney injury support nephrotoxic effects of HES to a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28867687/