Peer-reviewed veterinary case report
Dog's kidney function rapidly worsened after hydroxyethyl starch
By J. Bae et al.·Published in Journal of Veterinary Medical Science·2017·View original on Semantic Scholar →
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Original publication title: Rapid exacerbation of renal function after administration of hydroxyethyl starch in a dog
- Species:
- dog
Plain-English summary
A 4-year-old male Golden Retriever was given a treatment called hydroxyethyl starch (HES) to help with fluid buildup in his abdomen. Unfortunately, after a few days of this treatment, the dog's kidney function worsened significantly, leading to acute kidney injury. A closer examination of his kidneys showed damage caused by the HES. This case suggests that HES can be harmful to a dog's kidneys, and pet owners should discuss any potential risks with their veterinarian before starting such treatments.
People also search for: dog kidney injury treatment · hydroxyethyl starch side effects in dogs · Golden Retriever kidney problems
Abstract
Hydroxyethyl starches (HES) are commonly used synthetic colloidal solution in veterinary medicine. Despite of possible adverse effect to kidney injury in human, there is no report about nephrotoxic effects of HES in dogs. HES was administered to a Golden retriever (4-year-old, intact male) with ascites in order to increase plasma osmolality. Initially, the dog was mild azotemic, however, kidney function was rapidly deteriorated after several days of HES administration. Finally, histopathological examination revealed remarkable osmotic nephrosis. In the case reported herein, acute kidney injury was remarkably developed after HES administration. Clinical and histopathologic findings of acute kidney injury support nephrotoxic effects of HES to a dog.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/28867687