Peer-reviewed veterinary case report
Recent MUNE studies in animal models of motor neuron disease.
- Journal:
- Supplements to Clinical neurophysiology
- Year:
- 2009
- Authors:
- Shefner, Jeremy M
- Affiliation:
- Department of Neurology · United States
Abstract
MUNE provides valuable information when applied to animal models of motor neuron disease. It is potentially useful as a supplement to therapeutic trials on the SOD-1 transgenic mouse model and has been able to show increases in the functioning motor units in response to some stem cell transplantation. Even in models that have subtle or imperceptible phenotypes, MUNE can show reductions in motor unit compliment. Thus, it is a valuable addition to the armamentarium of investigative tools when studying models of motor unit loss.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20715383/