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Peer-reviewed veterinary case report

Dog's upper jaw rebuilt with custom titanium implants after cancer

By Fraile-Fernandez, Andrés et al.·Published in Veterinary research communications·2025·Veterinary Hospital Parla Sur, Spain·View original on PubMed

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Original publication title: Reconstruction of a rostral maxillary defect by two custom-made titanium implants following a partial maxillectomy for treatment of squamous cell carcinoma in a dog.

Species:
dog

Plain-English summary

A 7-year-old dog diagnosed with squamous cell carcinoma (a type of skin cancer) underwent surgery to remove part of its upper jaw. To help restore the dog's appearance and function, two custom-made titanium implants were placed during the surgery. The dog received additional treatments with toceranib phosphate and cimicoxib, which are medications that help fight cancer and manage pain. Remarkably, the dog has survived for over 1700 days after the surgery and is still doing well.

People also search for: dog mouth cancer treatment · titanium implants for dogs · squamous cell carcinoma in dogs · dog jaw surgery recovery

Abstract

This case report describes the reconstruction of a rostral maxillary defect by two custom-made titanium implants following a rostral partial maxillectomy for treatment of squamous cell carcinoma (SCC) in a seven-year-old dog. An incisional biopsy and CT scan were performed to establish the diagnosis, to plan possible surgery, and to assess the margins of the tumour. The patient had no radiographic signs of metastasis at the time of diagnosis. An oblique rostral partial maxillectomy with two custom-made titanium plates was chosen as an effective oncological treatment and to maintain the cosmetic appearance. A first custom implant was designed to support the cheek and lips, and a second implant was designed to replace part of the hard palate and serve as a base for the palatal mucosal flap. Surgical treatment combined with toceranib phosphate and cimicoxib therapy provided a survival time of at least 1700 days, as the patient is still alive at time of publication. Further research is warranted to determine the oncological and cosmetic efficacy of this surgical technique for treatment of SCC in a larger group of dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39820619/