Peer-reviewed veterinary case report
Dog with hard-to-control seizures caused by organic aciduria
By Platt, Simon et al.·Published in Journal of the American Animal Hospital Association·2007·Department of Small Animal Medicine, United States·View original on PubMed →
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Original publication title: Refractory seizures associated with an organic aciduria in a dog.
- Species:
- dog
Plain-English summary
A 6-month-old female Cavalier King Charles spaniel had seizures that were hard to manage with regular medications for a whole year. After extensive testing, vets discovered she had an organic aciduria, which means her body was excreting too much of a substance called hexanoylglycine. At 20 months old, her seizures became more manageable when they added levetiracetam to her existing treatments of potassium bromide and phenobarbital. With this combination, her seizures were finally under control.
People also search for: dog seizures treatment · Cavalier King Charles spaniel seizure control · organic aciduria in dogs
Abstract
A 6-month-old, female Cavalier King Charles spaniel exhibited seizures that were difficult to control with standard anticonvulsants over a 12-month period. The diagnosis of an organic aciduria with excessive excretion of hexanoylglycine was determined when the dog was 20 months old. Recurrent and cluster seizures were eventually controlled with the addition of levetiracetam to potassium bromide and phenobarbital.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17473023/