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Peer-reviewed veterinary case report

Causes of enlarged tracheobronchial lymph nodes in dogs on X-rays

By Jones, Brian G & Pollard, Rachel E·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2012·School of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Relationship between radiographic evidence of tracheobronchial lymph node enlargement and definitive or presumptive diagnosis.

Species:
dog
LymphomaMovement & jointsDogs

Plain-English summary

A group of 110 dogs showed enlarged tracheobronchial lymph nodes, which can indicate serious health issues. Most of these dogs (84%) had tumors, particularly lymphoma, while others had infections caused by fungi. The study found that conditions like histiocytic sarcoma and metastatic adenocarcinoma should also be considered when enlarged lymph nodes are seen on X-rays. The severity of the enlargement varied among the dogs, but the specific disease did not significantly affect the degree of enlargement. It's crucial for pet owners to discuss these findings with their veterinarian for proper diagnosis and treatment options.

People also search for: dog enlarged lymph nodes causes · lymphoma in dogs symptoms · fungal infections in dogs treatment

Abstract

Tracheobronchial lymphadenomegaly is commonly associated with lymphosarcoma and disseminated mycotic infection. Available data also suggest other pathologic causes of enlarged tracheobronchial lymph nodes. Our objective was to establish the distribution and prevalence of diseases that cause radiographically evident tracheobronchial lymphadenomegaly in a large population of dogs. Patients were divided into groups based on the methods of diagnoses with 25 having confirmed diagnoses and 85 with presumptive diagnoses. Of the 110 dogs in the study, 92 (84%) had neoplasia and 18 (16%) had infectious diseases. Infections were attributed to Coccidioides (12, 67%), Aspergillus (3, 17%), and 1 each (6%) to Nocardia, Penicillium, and Mycobacteriosis. Tumors were characterized as lymphoma (66, 60%) or nonlymphoid (26, 23.6%). Nonlymphomas in Group 1 included histiocytic sarcoma complex (16%), carcinoma (12%), adenocarcinoma (8%), osteosarcoma (8%), chemodectoma (4%), ganglioneuroblastoma (4%), and neuroendocrine (4%). The number of dogs with tracheobronchial lymphadenomegaly scores 1, 2, 3, 4, or 5 (with 5 being the greatest) was 8 (7%), 15 (14%), 30 (27%), 15 (14%), and 44 (38%), respectively. The results suggest that in addition to diagnoses of lymphoma and fungal infections, other neoplasms and in particular histiocytic sarcoma and metastatic adenocarcinoma, should be considered when tracheobronchial lymphadenomegaly is identified radiographically in dogs. When comparing the degree of tracheobronchial lymphadenopathy by disease category, there was no significant affiliation (P = 0.33).

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22818244/