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Peer-reviewed veterinary case report

Renal dysplasia and benign ureteropelvic polyps associated with hydronephrosis in a foal.

Journal:
Journal of the American Veterinary Medical Association
Year:
1994
Authors:
Jones, S L et al.
Affiliation:
Department of Medicine · United States
Species:
horse

Plain-English summary

A 4-month-old male Trakehner foal was having trouble growing, had blood in his urine, and showed some unusual hair growth. After some tests, including an ultrasound and surgery, it was found that he had a swollen kidney and ureter due to polyps (growths) blocking the urine flow. The doctors removed the affected kidney and ureter, and the examination showed that the foal had a condition called renal dysplasia (abnormal kidney development) likely present from birth. The treatment aimed to relieve the blockage and correct the kidney issues, but the exact cause of these problems is still unclear. The treatment was performed successfully, addressing the immediate issues caused by the polyps and hydronephrosis.

Abstract

A 4-month-old male Trakehner foal with a history of hematuria, poor growth, and abnormal hair was found to have unilateral hydronephrosis and hydroureter, as determined by ultrasonography and surgical exploration. Nephrectomy and ureterectomy were performed as treatment. Gross examination of the ureter and kidney revealed renal pelvic and ureteral polyps causing obstruction and subsequent hydronephrosis. The histologic features were consistent with renal dysplasia. The polyps and renal dysplasia were likely to be congenital, but the etiopathogenesis is not known. The finding that urinary outflow obstruction can disrupt nephrogenesis and lead to renal dysplasia supports the view that the polyps developed, blocked urine flow, and caused the hydronephrosis and renal dysplasia in the foal.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/8014095/