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Peer-reviewed veterinary case report

Urinary tract infection and kidney problem in Bull Mastiff puppy

By Abraham, L A et al.·Published in Australian veterinary journal·2003·University of Melbourne, Australia·View original on PubMed

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Original publication title: Renal dysplasia and urinary tract infection in a Bull Mastiff puppy.

Species:
dog

Plain-English summary

A 15-week-old female Bull Mastiff puppy was brought to the vet showing signs of chronic kidney failure, which can include increased thirst, frequent urination, and lethargy. After an ultrasound and lab tests, the vet found she had renal dysplasia (a kidney development issue) and a urinary tract infection. Unfortunately, the puppy's condition was complicated by inflammation and scarring in her kidneys. This case is particularly concerning as renal dysplasia has not been reported in Bull Mastiffs before, and it’s unclear if it was inherited or caused by an infection she had as a newborn.

People also search for: Bull Mastiff puppy kidney failure symptoms · renal dysplasia in puppies · urinary tract infection treatment in dogs

Abstract

Renal dysplasia and concurrent pyelonephritis were diagnosed in a 15-week-old female Bull Mastiff which presented with clinical signs compatible with chronic renal failure. Ultrasound examination was consistent with renal dysplasia and clinical pathology supported a diagnosis of chronic renal failure and urinary tract infection. Renal histological examination demonstrated inflammation and scarring with concurrent tubular dysplasia and persisting primitive glomeruli, although the presence of chronic inflammation complicated interpretation. It is uncertain whether renal dysplasia was inherited or due to a urinary tract infection acquired in the neonatal period. Renal dysplasia has not previously been reported in the Bull Mastiff breed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15080453/