Peer-reviewed veterinary case report
Dog with one missing kidney and kidney development problem causing
By Morita, T et al.·Published in Journal of comparative pathology·2005·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Renal dysplasia with unilateral renal agenesis in a dog.
- Species:
- dog
Plain-English summary
A 3-year-old dog was diagnosed with chronic kidney failure and had a missing right kidney and ureter. Blood tests showed signs of anemia and high levels of waste products, indicating the kidneys were not functioning properly. During the examination after the dog passed away, the remaining left kidney was found to be enlarged and had abnormal tissue development. Unfortunately, this condition is serious and can lead to significant health issues.
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Abstract
This report describes a renal dysplastic lesion associated with renal agenesis in a 3-year-old dog with chronic renal failure. Haematological examination revealed non-regenerative anaemia, azotaemia, increased creatinine and hyperphosphataemia. At necropsy, the right kidney and right ureter could not be identified. The left kidney was slightly enlarged, with a reduced cortico-medullary ratio. Histologically, the medulla of the left kidney had persistent mesenchyme and primitive tubules (tall pseudostratified columnar epithelium), dilated collecting ducts lined by flattened epithelium, and adenomatoid proliferation of cuboidal epithelium; fetal or immature glomeruli could not be identified. To our knowledge, this is the first report of a renal dysplastic lesion with unilateral agenesis in animals.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15899491/