Peer-reviewed veterinary case report
Bone disease linked to kidney failure in two dogs
By Cohen-Mivtach, Erez·Published in Journal of veterinary dentistry·2025·Karmiel Veterinary Center (KVC)·View original on PubMed →
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Original publication title: Renal Osteodystrophy in 2 Canine Patients.
- Species:
- dog
Plain-English summary
A young to middle-aged dog was brought in with oral problems and signs of kidney dysfunction. X-rays showed significant bone loss in the jaw, and further tests revealed advanced chronic kidney disease. The veterinarian emphasized the importance of early detection and managed the condition with dietary changes, phosphate binders, and supportive care. Unfortunately, the prognosis for dogs with advanced kidney disease is serious, highlighting the need for regular check-ups to catch issues early.
People also search for: dog kidney disease symptoms · oral problems in dogs · chronic kidney disease treatment for dogs
Abstract
This report presents 2 cases of renal osteodystrophy in young to middle-aged dogs, emphasizing the clinical presentation, diagnostic challenges, and therapeutic management. Both cases exhibited similar symptoms including oral abnormalities and renal dysfunction, with radiographic evidence revealing substantial bone resorption in the mandibles and maxillae. Histological analysis post-mortem confirmed advanced chronic kidney disease characterized by extensive fibrosis and glomerular abnormalities. The report underscores the critical importance of early detection of chronic kidney disease to mitigate the development of secondary hyperparathyroidism and subsequent renal osteodystrophy. These cases illustrate the complexities of diagnosing and managing renal osteodystrophy in dogs, highlighting the need for comprehensive diagnostic approaches combining clinical evaluation, radiographic imaging, and histopathological examination. Effective management strategies discussed include dietary modification, phosphate binding agents, and supportive care to alleviate clinical symptoms and slow progression of disease. The outcomes underscore the grave prognosis associated with advanced stages of chronic kidney disease and emphasize the significance of proactive screening and early intervention in mitigating renal osteodystrophy in canine patients.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40025761/