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Peer-reviewed veterinary case report

Cat kidney tumor producing renin hormone found in male cat

By Brown, P et al.·Published in Journal of comparative pathology·2019·University of Bristol, United Kingdom·View original on PubMed

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Original publication title: Renin-producing Tumour in the Kidney of a Cat.

Species:
cat

Plain-English summary

A neutered male cat was found to have a tumor in his right kidney after showing signs of immune-mediated hemolytic anemia, which can cause weakness and pale gums. Tests revealed that the tumor was malignant and produced a hormone called renin, which can affect blood pressure. Unfortunately, the cat did not survive due to the severity of the condition. This case highlights the importance of thorough examinations when a cat shows unusual symptoms like anemia.

People also search for: cat kidney tumor symptoms · cat anemia treatment · signs of kidney cancer in cats

Abstract

Clinical and post-mortem examination of an adult neutered male cat with immune-mediated haemolytic anaemia revealed suspected nodules of tumour tissue in the cortex of the right kidney. Cytology and histopathology indicated a malignant renal tumour of undetermined type. Immunohistochemistry confirmed renin production by a proportion of the tumour cells. The lesion may represent a renal adenocarcinoma producing renin or a tumour of juxtaglomerular cells ('reninoma').

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31375161/