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Peer-reviewed veterinary case report

Dog with kidney protein loss linked to Babesia gibsoni infection gets

By Slade, Dennis J et al.·Published in Journal of the American Animal Hospital Association·2011·Department of Clinical Studies, United States·View original on PubMed

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Original publication title: Resolution of a proteinuric nephropathy associated with Babesia gibsoni infection in a dog.

Species:
dog

Plain-English summary

A 4-year-old male Labrador retriever was brought to the vet because he wasn't eating, seemed tired, had diarrhea, and was drinking and urinating more than usual. Tests showed he had kidney problems likely caused by a Babesia gibsoni infection, which is a type of parasite. The dog was treated with a combination of medications, including azithromycin and corticosteroids. After three months of treatment, he was back to his normal self, and all signs of the infection and kidney issues were gone.

People also search for: dog kidney disease symptoms · Labrador diarrhea treatment · Babesia gibsoni infection in dogs

Abstract

A 4 yr old male castrated Labrador retriever was evaluated for a short history of inappetance, lethargy, small-bowel diarrhea, polyuria, and polydipsia. Clinicopathologic abnormalities were consistent with protein-losing nephropathy and renal azotemia. Expansive infectious disease testing implicated Babesia gibsoni via whole blood polymerase chain reaction. Renal histopathology results were consistent with membranoproliferative glomerulonephritis and immune complex deposition. The dog was treated with azithromycin, atovaquone, and one dose of corticosteroids/cyclophosphamide. Three months after therapy was completed, the dog was clinically healthy, and all clinicopathologic abnormalities (including Babesia species polymerase chain reaction) had resolved. Atypical presentations of Babesia gibsoni should be considered with proteinuric nephropathy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22058361/