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Peer-reviewed veterinary case report

Cat with eye movement problems from orbital tumor and treatment

By Thomasy, Sara M et al.·Published in Veterinary ophthalmology·2013·Veterinary Medical Teaching Hospital School of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Restrictive orbital myofibroblastic sarcoma in a cat--cross-sectional imaging (MRI & CT) appearance, treatment, and outcome.

Species:
cat

Plain-English summary

A 16-year-old spayed female cat was brought in for eye problems, including difficulty closing her eyes and severe irritation in both eyes. After various treatments, including medications and temporary eyelid surgery, her condition did not improve. Eventually, surgery to remove the affected eye tissue was performed, but the cat later showed signs of weight loss and jaw pain. Sadly, further tests revealed an aggressive cancer in her eye area, and the decision was made to euthanize her. This case highlights the importance of early and aggressive treatment for certain eye tumors in cats.

People also search for: cat eye problems · feline cancer treatment · why is my cat losing weight · cat jaw pain causes · cat eyelid surgery recovery

Abstract

A 16-year-old spayed female cat was evaluated for lagophthalmos and chronic exposure keratitis in both eyes. Ophthalmic examination revealed upper and lower eyelid entropion of the left eye (OS) and markedly decreased retropulsion, restricted eye movement, marked episcleral congestion, and severe keratitis of both eyes (OU). Magnetic resonance imaging of both orbits revealed extensive, irregular, contrast-enhancing tissue without evidence of osteolysis considered compatible with diffuse inflammatory tissue. Feline herpesvirus DNA was not detected in conjunctival samples. Partial temporary tarsorrhaphies were placed OU, and the cat was treated with topically administered erythromycin ointment OU, orally administered famciclovir and prednisolone, and sublingually administered buprenorphine. Little improvement was noted after 2 weeks. Six weeks after initial presentation, a left exenteration was performed and histopathology was consistent with idiopathic sclerosing orbital pseudotumor (ISOP). Ten weeks after initial presentation, the patient represented for weight loss and jaw pain. Computed tomography demonstrated disease progression in the right orbit and the patient was euthanized. Histopathology of the decalcified skull revealed an aggressive and highly infiltrative mass involving the right orbit with extension to the maxilla, hard palate, nasal cavity and gingiva most consistent with feline restrictive orbital myofibroblastic sarcoma (FROMS). Clinical data from this patient support the reclassification of ISOP as FROMS. MRI and CT may provide supportive evidence for FROMS, but histopathology is necessary for definitive diagnosis. Aggressive and early surgical treatment, including bilateral exenteration, with adjunctive radiotherapy and/or chemotherapy should be considered for patients with FROMS.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23281709/