Peer-reviewed veterinary case report
Prednisolone helps cats with lymphocytic cholangitis live longer than
By Otte, C M A et al.·Published in Veterinary journal (London, England : 1997)·2013·Department of Clinical Sciences of Companion Animals, Netherlands·View original on PubMed →
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Original publication title: Retrospective comparison of prednisolone and ursodeoxycholic acid for the treatment of feline lymphocytic cholangitis.
- Species:
- cat
Plain-English summary
A group of 26 cats with lymphocytic cholangitis, a liver condition, showed symptoms like weight loss, jaundice (yellowing of the skin), loss of appetite, vomiting, and lethargy. Most of these cats were male, and the Norwegian Forest Cat breed was particularly affected. The cats were treated with either prednisolone, a steroid medication, or ursodeoxycholic acid (UDCA), which helps with liver function. The results indicated that cats treated with prednisolone had a longer survival time compared to those receiving UDCA.
People also search for: cat liver disease treatment · feline lymphocytic cholangitis symptoms · prednisolone for cats liver problems
Abstract
A retrospective study was performed to evaluate the effect of treatment with prednisolone or ursodeoxycholic acid (UDCA) on the survival times of 26 cats with lymphocytic cholangitis, and to determine prognostic factors. Most affected cats were males (76.9%, P=0.006) and a breed predisposition for the Norwegian Forest Cat was demonstrated (P=0.021). Clinical signs included weight loss, icterus, anorexia, vomiting, and listlessness. Blood analyses revealed elevated hepatic enzymes, bile acids and hypergammaglobulinaemia. Breed, sex, and therapeutic regimen were significantly associated with survival times. Prednisolone treatment resulted in a statistically longer survival time compared to UDCA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22840210/