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Peer-reviewed veterinary case report

Doxorubicin treatment outcomes for cats with mammary cancer

By Novosad, C Andrew et al.·Published in Journal of the American Animal Hospital Association·2006·Donaldson-Atwood Cancer Clinic and Flaherty Comparative Oncology Laboratory, United States·View original on PubMed

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Original publication title: Retrospective evaluation of adjunctive doxorubicin for the treatment of feline mammary gland adenocarcinoma: 67 cases.

Species:
cat

Plain-English summary

A group of 67 cats diagnosed with mammary gland cancer received surgery followed by a chemotherapy drug called doxorubicin to help manage their condition. On average, these cats lived for about 448 days after treatment, with a disease-free period of around 255 days before the cancer returned. Factors like the type of tumor and whether it spread to other areas of the body influenced how long the cats lived and how long they stayed cancer-free. This treatment approach showed promise in extending survival for cats with this type of cancer.

People also search for: cat mammary cancer treatment · doxorubicin for cats · feline cancer survival rates

Abstract

Medical records for 67 cats with histologically confirmed mammary gland adenocarcinomas treated with adjunctive doxorubicin from June 1994 through December 2002 were reviewed. Data were examined to evaluate factors influencing disease-free interval (DFI) and survival time. The Kaplan-Meier median survival time of cats that received surgery and doxorubicin was 448 days. The Kaplan-Meier median DFI was 255 days. Significant univariate prognostic factors for DFI included histological subtype, completion of initial chemotherapy, development of metastatic disease, and location of metastatic disease. Significant univariate prognostic factors for survival included tumor volume, the development of metastatic disease, and location of metastatic disease.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16527911/