Peer-reviewed veterinary case report
How full-thickness stomach and intestine biopsies help diagnose
By Kleinschmidt, S et al.·Published in Veterinary pathology·2006·Department of Pathology, Germany·View original on PubMed →
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Original publication title: Retrospective study on the diagnostic value of full-thickness biopsies from the stomach and intestines of dogs with chronic gastrointestinal disease symptoms.
- Species:
- dog
Plain-English summary
A group of 64 dogs with ongoing gastrointestinal issues underwent full-thickness biopsies of their stomach and intestines to find out what was causing their symptoms. The results showed that many of the dogs had conditions like intestinal lymphangiectasia, eosinophilic colitis, or even intestinal T-cell lymphoma. The full-thickness biopsies provided clearer diagnoses compared to smaller samples taken during endoscopy. This means that if your dog has chronic stomach or intestinal problems, a full-thickness biopsy might help your vet identify the issue more accurately and guide treatment.
People also search for: dog chronic gastrointestinal disease · dog intestinal lymphoma treatment · dog biopsy results explained
Abstract
An evaluation of histologic findings in full-thickness biopsies from the gastrointestinal tract (GIT) from 64 dogs with chronic GIT disease symptoms was performed. In the majority of cases (38/64; 59%), intestinal lymphangiectasia and mucosal edema of unknown etiology were present. In 10 dogs (16%) an eosinophilic colitis, either alone or together with gastritis and/or enteritis, was found. In 5 dogs (8%) lymphocytic-plasmacytic enteritis or enterocolitis was diagnosed. Five dogs (8%) had an intestinal T-cell lymphoma. Samples from the remaining cases were histologically normal or did not allow for a final diagnosis. In contrast to reports about findings in endoscopic biopsies (which often are of varying quality or inadequate for diagnosis), in the majority of cases of this study, examination of full-thickness biopsies from the GIT allowed us to make a definitive histopathologic diagnosis. Furthermore, the study revealed that transmural biopsies are very helpful for diagnosing lymphoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17099159/