Peer-reviewed veterinary case report
Risk factors for bone cancer in large and giant dogs in western Canada
By Williams, Kimberly et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2023·Department of Small Animal Clinical Sciences (Williams, Canada·View original on PubMed →
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Original publication title: Risk factors for appendicular osteosarcoma occurrence in large and giant breed dogs in western Canada.
- Species:
- dog
Plain-English summary
A study looked at large and giant breed dogs, like Rottweilers and Great Danes, to understand why some develop appendicular osteosarcoma (a type of bone cancer). It found that dogs that were spayed or neutered, overweight, or had a history of limping were more likely to get this cancer. The research suggests that maintaining a healthy weight and addressing any lameness issues could help reduce the risk of this serious condition.
People also search for: dog bone cancer symptoms · Rottweiler osteosarcoma risk factors · Great Dane limping treatment
Abstract
OBJECTIVE: Risk factors for the development of canine appendicular osteosarcoma (OSA) have been investigated in numerous studies, but with contradictory results. The aim of this study was to analyze weight, age, breed, sex, neuter status, body condition score, and previous lameness in a population of large and giant breed dogs in western Canada with and without appendicular OSA. ANIMALS AND PROCEDURE: Medical records of 227 large or giant breed dogs diagnosed with appendicular OSA were compared to records from a control population of 454 large and giant breed dogs from the years 2000 to 2020. RESULTS: Gonadectomized dogs, body condition score (BCS), and a history of lameness condition(s) (other than OSA) were associated with increased odds for presentation with OSA. Breeds shown to have increased odds for appendicular OSA occurrence included Rottweilers and Great Danes relative to Labrador retrievers. CONCLUSION AND CLINICAL RELEVANCE: Obesity and lameness appear to be independently associated with appendicular osteosarcoma. This study demonstrated that spayed females had the greatest risk compared to other sex and neuter status combinations; further investigation of these factors would be beneficial.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36733647/