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Peer-reviewed veterinary case report

Antimicrobial peptide treatment safe and effective for dog

By Alberola, J et al.·Published in Antimicrobial agents and chemotherapy·2004·Departament de Farmacologia, Spain·View original on PubMed

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Original publication title: Safety and efficacy of antimicrobial peptides against naturally acquired leishmaniasis.

Species:
dog

Plain-English summary

A dog with leishmaniasis, a serious parasitic disease, was treated with a synthetic antimicrobial peptide called Oct-CA(1-7)M(2-9). This treatment was found to be both safe and effective in helping the dog recover from the disease. Leishmaniasis can be challenging to treat, but this new approach shows promise for improving outcomes in affected dogs.

People also search for: dog leishmaniasis treatment · antimicrobial peptides for dogs · safe treatments for dog parasites

Abstract

Leishmaniases, which are important causes of morbidity and mortality in humans and dogs, are extremely difficult to treat. Antimicrobial peptides are rarely used as alternative treatments for naturally acquired parasitic diseases. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14742227/