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Peer-reviewed veterinary case report

Safety and efficacy of antimicrobial peptides against naturally acquired leishmaniasis.

Journal:
Antimicrobial agents and chemotherapy
Year:
2004
Authors:
Alberola, J et al.
Affiliation:
Departament de Farmacologia · Spain
Species:
dog

Abstract

Leishmaniases, which are important causes of morbidity and mortality in humans and dogs, are extremely difficult to treat. Antimicrobial peptides are rarely used as alternative treatments for naturally acquired parasitic diseases. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/14742227/