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Peer-reviewed veterinary case report

Bone sarcoma developing years after radiotherapy in two dogs

By Mellanby, R. J. et al.·Published in Veterinary and Comparative Oncology·2003·View original on Crossref

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Original publication title: Sarcoma development after radiotherapy in two dogs

Species:
dog

Plain-English summary

A 7-year-old mixed breed dog and a 9-year-old Labrador were both treated with radiation therapy after having tumors removed. Several years later, both dogs developed bone tumors in the areas that had been treated with radiation. This type of tumor, known as a sarcoma, is a rare side effect of radiation therapy in dogs, although it's more commonly seen in humans. Unfortunately, the development of these tumors highlights a potential long-term risk of radiation treatment for pets.

People also search for: dog bone tumor after radiation · sarcoma in dogs · side effects of dog cancer treatment · dog tumor treatment options

Abstract

AbstractTwo dogs were treated with a hypofractionated course of radiotherapy following surgical excision of an intermediate grade mast cell tumour and a round cell tumour, respectively. Both dogs developed a sarcoma of the bone, within the irradiated site, several years after the initial radiotherapy treatment. Bone tumours arising within a previously irradiated area are well‐recognized late radiotherapy side‐effect in humans but have been reported infrequently in dogs. These are the first case reports to describe bone sarcomas in the appendicular skeleton at a site, which had been previously treated by a hypofractionated course of radiotherapy for an unrelated tumour.

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Original publication on Crossref: https://doi.org/10.1046/j.1476-5829.2003.00014.x