Peer-reviewed veterinary case report
Scientific evidence on cannabidiol (CBD) for dog and cat health
By Corsato Alvarenga, Isabella et al.·Published in Annual review of animal biosciences·2023·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Scientific Validation of Cannabidiol for Management of Dog and Cat Diseases.
- Species:
- dog
Plain-English summary
A study found that cannabidiol (CBD), a compound from the cannabis plant, may help manage various health issues in dogs and cats, including arthritis pain, itching, and seizures. It appears to be safe with few side effects when given at proper doses. Some dogs showed improvement in their symptoms after receiving CBD, but more research is needed to fully understand its effectiveness for each condition and its potential benefits for anxiety and aggression. Overall, CBD could be a promising alternative treatment for pets with certain health problems.
People also search for: CBD for dog arthritis · cat itching treatment · dog seizure management with CBD
Abstract
Cannabidiol (CBD) is a non-psychotropic phytocannabinoid of the plantL. CBD is increasingly being explored as an alternative to conventional therapies to treat health disorders in dogs and cats. Mechanisms of action of CBD have been investigated mostly in rodents and in vitro and include modulation of CB1, CB2, 5-HT, GPR, and opioid receptors. In companion animals, CBD appears to have good bioavailability and safety profile with few side effects at physiological doses. Some dog studies have found CBD to improve clinical signs associated with osteoarthritis, pruritus, and epilepsy. However, further studies are needed to conclude a therapeutic action of CBD for each of these conditions, as well as for decreasing anxiety and aggression in dogs and cats. Herein, we summarize the available scientific evidence associated with the mechanisms of action of CBD, including pharmacokinetics, safety, regulation, and efficacy in ameliorating various health conditions in dogs and cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36790884/