Peer-reviewed veterinary case report
Secondary lymphoma in three dogs after chemotherapy treatment
By Kim, Jeong Mi et al.·Published in Veterinary medicine and science·2021·College of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Secondary lymphoma development after chemotherapy in three dogs.
- Species:
- dog
Plain-English summary
An 11-year-old spayed female Shih-Tzu developed swollen lymph nodes about 25 months after chemotherapy for breast cancer. Another 15-year-old spayed female Shih-Tzu showed similar symptoms just three months after treatment for a gastrointestinal tumor. Lastly, an 8-year-old male Mongrel had lymph node swelling 14 months after receiving treatment for a mast cell tumor. All three dogs were diagnosed with high-grade T-cell lymphoma after their initial cancer treatments. This highlights the importance of monitoring dogs for new health issues after cancer treatment, as secondary lymphoma can develop.
People also search for: dog swollen lymph nodes after cancer treatment · Shih-Tzu lymphoma symptoms · secondary cancer in dogs after chemotherapy
Abstract
Lymphoma is widely recognized in veterinary medicine. However, studies focused on secondary lymphoma after chemotherapy do not exist in veterinary medicine. An 11-year-old, spayed female Shih-Tzu dog was diagnosed with mammary gland carcinoma. Twenty-five months after carboplatin treatment, the dog developed generalized lymphadenopathy (GL), diagnosed as high-grade T-cell lymphoma by immunohistochemistry. Another spayed female Shih-Tzu dog who was 15-year-old had biopsy-induced gastrointestinal stromal tumour. Three months after being treated with Toceranib, the dog developed GL that was diagnosed by PCR for antigen receptor rearrangement as T-cell lymphoma. An eight-year-old, castrated male Mongrel dog was diagnosed with mast cell tumour. The dog was treated with vinblastine, but 14 months later, GL was revealed. Fine-needle aspiration indicated lymphoma. The owner declined to investigate the cell lineage. All three dogs developed GL after chemotherapy. We suggest that secondary lymphoma can develop in dogs after chemotherapy for a primary cancer, and thus long-term follow-up is necessary.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33713569/