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Peer-reviewed veterinary case report

Dog with kidney infection causing high red blood cells

By Kessler, M·Published in The Journal of small animal practice·2008·Tierklinik Hofheim, Germany·View original on PubMed

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Original publication title: Secondary polycythaemia associated with high plasma erythropoietin concentrations in a dog with a necrotising pyelonephritis.

Species:
dog

Plain-English summary

An 11-year-old mixed breed dog was brought to the vet because he was not eating, seemed lethargic, and had blood in his urine. Tests showed he had a high number of red blood cells and elevated levels of a hormone called erythropoietin, which can indicate kidney issues. An ultrasound revealed a kidney mass, and after surgery to remove the affected kidney, the dog's blood values returned to normal. This case highlights how a serious kidney infection can lead to increased red blood cell production in dogs.

People also search for: dog blood in urine · dog kidney infection treatment · why is my dog not eating and lethargic

Abstract

An 11-year-old mixed breed dog was presented with anorexia, apathy and intermittent macrohaematuria, absolute polycythaemia (packed cell volume, 80 per cent; red blood cell, 12.2 x 10(6)/microl) and elevated erythropoietin concentrations. A renal mass was detected by ultrasonography and, following total nephrectomy, diagnosed as necrotising pyelonephritis. After surgery, the haematological parameters and erythropoietin values returned to normal, suggesting that the pyelonephritis was the cause of the polycythaemia. While secondary polycythaemia because of a non-neoplastic condition of the kidneys occasionally occurs in human beings, it has only extremely rarely been reported in dogs. This is the first case report of a unilateral pyelonephritis causing secondary polycythaemia in a dog.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18482331/