Peer-reviewed veterinary case report
Seizures in juvenile dogs after stopping IV anesthesia
By Dreese, Kaitlyn et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2024·University of Pennsylvania School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Seizures in 3 juvenile dogs after intravenous anesthetic drug withdrawal during weaning from mechanical ventilation suspected to be a sign of iatrogenic withdrawal syndrome.
- Species:
- dog
Plain-English summary
Three young dogs, around 3 months old, started having seizures after being taken off a breathing machine and stopping an anesthetic drug called midazolam. This reaction is thought to be due to withdrawal from the medication they had been receiving during their treatment for lung issues. Each dog was given medication to control the seizures, and thankfully, none had further seizures after they were sent home. It's important for pet owners to be aware that young dogs may experience withdrawal symptoms after long-term anesthesia.
People also search for: puppy seizures after anesthesia · dog withdrawal symptoms from anesthesia · juvenile dog seizure treatment
Abstract
OBJECTIVE: To describe seizure activity in juvenile dogs successfully weaned from long-term mechanical ventilation. CASE SERIES SUMMARY: Three juvenile dogs (all approximately 3 months old) underwent long-term mechanical ventilation with IV anesthesia for suspected noncardiogenic pulmonary edema. Within 24 hours of extubation and within 10 hours of discontinuing midazolam continuous infusions, all dogs experienced seizures, which is 1 sign of iatrogenic withdrawal syndrome. Each dog was treated with an anticonvulsant protocol, and none experienced seizures after being discharged. NEW OR UNIQUE INFORMATION PROVIDED: Each dog received IV anesthesia, including fentanyl, dexmedetomidine, midazolam, and propofol, during mechanical ventilation and subsequently experienced seizures after successful weaning from mechanical ventilation. Juvenile dogs may be at risk for seizures after weaning from mechanical ventilation and IV anesthesia. Neurological monitoring and further research into an appropriate weaning protocol may prove beneficial in juvenile dogs requiring prolonged anesthesia.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38407536/