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Peer-reviewed veterinary case report

Yorkshire Terrier dog with testicle tumor causing high estrogen

By Kim, Okjin & Kim, Kyung-Suk·Published in The Journal of veterinary medical science·2005·Department of Laboratory Animal Sciences, South Korea·View original on PubMed

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Original publication title: Seminoma with hyperesterogenemia in a Yorkshire Terrier.

Species:
dog

Plain-English summary

An 8-year-old male Yorkshire Terrier was brought to the vet because he had a poor appetite and was losing hair in patches. Tests showed that one of his testicles was abnormally enlarged and firm, and surgery was performed to remove both testicles. The results confirmed he had a seminoma, a type of testicular tumor, and high levels of estrogen in his blood, which likely contributed to his hair loss. After the surgery, the dog's symptoms were addressed, but ongoing monitoring would be important for his overall health.

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Abstract

A male 8-year-old Yorkshire Terrier dog with unilateral cryptorchism was presented for investigation of reduced appetite and multifocal alopecia. Abdominal sonography and radiography demonstrated abnormal enlargement of left testicle in abdominal cavity. Both of the retroperitoneal cryptorchid testicle and the other contralateral testicle were removed surgically. The concentrations of testosterone and estradiol in blood collected from the jugular vein and the two spermatic veins were evaluated and the results revealed high estradiol concentration. The retroperitoneal cryptorchid testicle was enlarged, firm, bulging sphere mass. The cut surface revealed homogeneous white color and lobulation by septa. The contralateral testicle in scrotum showed atrophic testicle and enlarged epididymis. Histopathologically, the retroperitoneal cryptorchid testicle was diagnosed as seminoma. We thought that hyperesterogenemia and alopecia in this case was probably related with his seminoma, although high correlations between Sertoli cell tumor and alopecia have been reported. To our knowledge, this report may be a rare case of seminoma with hyperesterogenemia and alopecia.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15699609/