Peer-reviewed veterinary case report
Cross-reactions in dog blood tests for leishmaniasis and other
By Zanette, Maurício Franco et al.·Published in Revista da Sociedade Brasileira de Medicina Tropical·2014·Pó·View original on PubMed →
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Original publication title: Serological cross-reactivity of Trypanosoma cruzi, Ehrlichia canis, Toxoplasma gondii, Neospora caninum and Babesia canis to Leishmania infantum chagasi tests in dogs.
- Species:
- dog
Plain-English summary
A group of dogs was tested for leishmaniasis, a serious disease caused by a parasite, and researchers found that some dogs with other infections like Ehrlichia or Babesia could show false positive results on leishmaniasis tests. Out of 57 dogs tested, 24 showed positive results for leishmaniasis using different testing methods, but this could be due to their other infections. This means that if your dog has been tested for leishmaniasis and has other health issues, the results might not be accurate. It's important to discuss any test results with your veterinarian to understand what they mean for your dog's health.
People also search for: dog leishmaniasis symptoms · false positive leishmaniasis test dog · Ehrlichia canis treatment in dogs
Abstract
INTRODUCTION: The aim of this study was to evaluate the serological cross-reactivity between Leishmania sp. and other canine pathogens. METHODS: Positive serum samples for Ehrlichia canis, Babesia canis, Toxoplasma gondii, Neospora caninum and Trypanosoma cruzi were tested using three serological methods enzyme linked immunosorbent assay (ELISA), indirect immunofluorescent antibody test (IFAT) and Kalazar Detect™, for canine visceral leishmaniasis. RESULTS: Of the 57 dog samples tested, 24 (42.1%) tested positive using one of the three serological methods: 10/57 (17.5%) for ELISA, 11/57 (19.3%) for IFAT and 3/57 (5.3%) for Kalazar Detect™. CONCLUSIONS: Our results demonstrated that the presence of other infectious agents may lead to cross-reactivity on leishmaniasis serological tests.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24603745/