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Peer-reviewed veterinary case report

Alpha 1-acid glycoprotein levels in cats with lymphoma

By Correa, S S et al.·Published in Journal of the American Animal Hospital Association·2001·Department of Veterinary Clinical Sciences, United States·View original on PubMed

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Original publication title: Serum alpha 1-acid glycoprotein concentration in cats with lymphoma.

Species:
cat

Plain-English summary

A group of nine cats with lymphoma had their blood tested for a protein called alpha 1-acid glycoprotein (AGP) before and after starting chemotherapy. The results showed that these cats had higher levels of AGP compared to healthy cats, but the levels did not change significantly after treatment. Unfortunately, measuring AGP levels did not help predict how well the cats responded to treatment or how long they would survive. This means that while AGP levels were higher in cats with lymphoma, they weren't useful for tracking the disease's progress or success of the therapy.

People also search for: cat lymphoma treatment · high AGP levels in cats · cat cancer survival rates

Abstract

Serum alpha 1-acid glycoprotein (AGP) concentrations were evaluated in nine cats with lymphoma. Twenty-five healthy cats were used as controls. Blood samples were obtained from cats with lymphoma prior to induction chemotherapy, one week following induction, at complete response, and at monthly intervals. The median pretreatment AGP concentration for the nine cats with lymphoma was significantly higher than the median AGP concentration for the 25 control cats. Remission serum AGP concentration was not significantly different from the pretreatment AGP concentration in the cats with lymphoma. Serum AGP concentrations provided no useful information regarding response or survival in cats with lymphoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11300522/